Transient efficacy of pulse pamidronate treatment in active spondylarthropathies: an open study of 35 cases.

Efficacy of topical immunotherapy of extensive and/or chronic Alopecia Areata with Diphencyprone

Background: Highly variable results of topical immunotherapy with Diphencyprone (DPC) in the treatment of Alopecia areata have been reported so far. Objective: The purpose of this study was to evaluate the efficacy and tolerability of DPC in the treatment of severe and chronic chronic Alopecia areata. Patients and Methods: 28 patients (16 female and 12 male, 10-35 years old, mean age 25 years) ...

Single-Agent Therapy for Low Risk Gestational Trophoblastic Neoplasia (LRGTN): A Preliminary Report on a Randomized Clinical Trial to Compare Pulse-Methotrexate versus Pulse-Dactinomycin

The efficacy of single-agent chemotherapy for patients with low risk gestational trophoblastic neoplasia (LRGTN) with methotrexate or dactinomycin is well established, but efforts continue to reduce the toxicity, the patients time and cost of treatment. In a randomized clinical trial, we evaluated and compared the efficacy, toxicity and cost effectiveness of pulse-methotrexate versus pulse-dact...

Efficacy and Safety of Aripiprazole for Treatment of Irritability in Children with Autistic Disorder: An Open-Label Study

Efficacy of superficial peeling with 70% Glycolic Acid in treatment of Acne

Background: Comedone formation has an essential role in pathophysiology of acne, therefore destroying of comedones and preventing of comedone formation is very important in acne treatment. Objective: To determine the effect of superficial peeling with 70% glycolic acid in the improvement of acne. Patients and Methods: In this open clinical trial without control group, 30 patients with acn...

Open Drainage in Chronic Subdural Hematomas: A Prospective Study of 189 Cases

Background & Importance: Chronic subdural hematoma (CSH) is one of the most frequent intracranial hemorrhages in adults. However, gold standard treatment of CSH is not yet defined. Since the 80’s, closed drainage is a standard among techniques using drains because the open type has been incriminated in high rates of postoperative infections. However, closed drainage requires mat...